St Richard's Hospital Vascular Unit                         Royal West Sussex NHS Trust


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Arterial Athersclerosis                                       

Atherosclerosis is a Greek term which translates as "hardened gruel or porridge". The term describes the material found inside the affected arteries. The process of atherosclerosis occurs through stages that can span over many years. It involves the abnormal laying down of fat, calcium, white blood cells, platelets and other blood clotting components on the inside of arteries. Atherosclerosis formation is usually facilitated by other risk factors.

Atherosclerotic depositions, which are called plaques, can lead to progressive narrowing and eventually blockage of the affected artery. The blockage of a main artery in this fashion is usually gradual and insidious. 

Occasionally, a part of a plaque sheds off and suddenly blocks the affected artery or floats with the blood until it becomes lodged at the opening of a small branch. This can suddenly stop the flow of blood with potentially serious consequences if not treated promptly . Brain strokes and heart attacks are two examples for such an event.


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Last updated: January 16, 2005.                                           
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